The Smith & Wesson 500 is one powerful looking handgun on video. This Youtuber filmed herself shooting one with one hand. Here's the youtube video link.
The most impressive part starts at about the 00:38 mark where we see a close up profile of the forearm and gun in slow motion as it fires. The lady's *jangly jewelry blocks the view, but if what we see is real, the space between the hand and the forearm got seriously compressed for a few milliseconds.
*Not actually jewelry, more likely multiple commemorative wristbands.